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Coal Tar Psoriasis: The Science of Slowing Cell Turnover

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By Ana Cristina Vazquez Martinez

Jan/15/2026

Reading time: 5 minutes

Coal Tar Psoriasis

In the field of dermatology, we often talk about psoriasis as an immune-mediated disease. But to truly understand the physical manifestation—the plaques, the scales, the thickening—we must look at it as a kinetic problem. It is a problem of speed.

In a healthy epidermis, the life cycle of a skin cell (keratinocyte) takes approximately 28 to 30 days. It is a slow, orderly migration from the basal layer to the surface, where it sheds invisibly. In psoriatic skin, this process is hijacked. The immune system sends faulty signals that cause these cells to mature and reach the surface in just 3 to 4 days.

The result is a traffic jam of immature cells piling up on top of one another. This is what you see as a silvery plaque. It isn’t just “dry skin”; it is hyperproliferation.

For decades, the “gold standard” in addressing this kinetic error has been Coal Tar Psoriasis treatments. While modern biologics target the immune system systemically, Coal Tar remains one of the most effective topical agents for addressing the physical pathology locally. Today, we will dissect the pharmacodynamics of Dermabon’s 2% Coal Tar formula and why, from a clinical perspective, it remains a frontline defense.

How Does 2% Coal Tar Work on Your Skin?

To explain the mechanism of action of Coal Tar, we must use two specific medical terms: Antimitotic and Keratoplastic.

When patients ask about the science behind Coal Tar Psoriasis treatments, I explain that it functions as a brake system for the skin. The active compounds in coal tar (which include thousands of hydrocarbons) penetrate the epidermis and interact directly with the DNA of the keratinocytes.

1. The Antimitotic Effect (Stopping the Speed)

Research indicates that Coal Tar inhibits DNA synthesis in the skin cells. By suppressing this synthesis, it effectively tells the cells to stop dividing so rapidly. It forces the skin to return to a normal rhythm of regeneration.

This is the core of the solution: Dermabon slows down accelerated cell turnover. By reducing the mitotic rate (cell division), the skin stops producing the excess tissue that forms the plaque.

2. The Keratoplastic Effect (Normalizing the Layers)

Simultaneously, Coal Tar helps to correct the abnormal keratinization. It assists the skin in shedding the dead cells properly rather than letting them adhere to each other. This reduces the thickness of the stratum corneum (the outer layer), leading to thinner, flatter lesions and, eventually, clear skin.

Technical Data: Why 2%? In clinical formulation, concentration matters. A concentration of 2% Coal Tar is considered the therapeutic “sweet spot” for over-the-counter treatments. It provides sufficient potency to exert these antimitotic effects without the high risk of irritation or the intense mess associated with crude coal tar preparations used in hospitals (Goeckerman regimen).

Treat the cause from the root. Do not just moisturize the scale; stop the production of it. Buy Dermabon with 2% Coal Tar technology online.

Proven Efficacy Without the Risks of Steroids

As a researcher, one of my primary concerns with long-term disease management is the side effect profile of the treatment.

Topical corticosteroids are anti-inflammatory, yes. They reduce redness quickly by constricting blood vessels. However, they do not fundamentally “teach” the skin to behave normally; they suppress it.

The long-term use of steroids leads to skin atrophy (thinning), striae, and tachyphylaxis (where the drug stops working).

Coal Tar Psoriasis treatments differ significantly here. Coal Tar does not cause skin atrophy. It can be used for extended periods to maintain remission (clear skin) without damaging the structural integrity of the dermis.

The “All-in-One” Therapeutic Solution

Dermabon is unique because it integrates this potent medical agent into a vehicle—soap—that also manages hygiene.

  • It cleanses: Removing surface bacteria (Staphylococcus aureus colonization is common in psoriasis).
  • It medicates: Delivering the 2% active ingredient.
  • It soothes: Reducing the pruritus (itching) via its mild anaesthetic properties on nerve endings.

For a patient, this means replacing a complex regimen of creams and washes with a single, scientifically validated step.

Optimal Application for Maximum Results

In pharmacology, the effectiveness of a topical drug is dependent on bioavailability and absorption. A common mistake patients make with Coal Tar Psoriasis soaps is washing it off too quickly.

For the coal tar to inhibit DNA synthesis and slow down the cell turnover, it must penetrate the thickened plaque.

The Protocol:

  1. Lather: Apply the soap to the affected area.
  2. Wait: This is the critical clinical step. Leave the lather on the skin for 3 to 5 minutes.
  3. Rinse.

This dwell time allows the active ingredient to navigate through the layers of dead skin and reach the viable epidermis where the rapid division is happening. Washing it off immediately turns a medical treatment into a simple cosmetic wash, negating its benefits.

Conclusion

In an era of influencers and unverified “natural” claims, it is crucial to return to evidence-based dermatology. Psoriasis is a complex, chronic disease driven by cellular chaos. To manage it, you need a regulator.

Coal Tar Psoriasis therapy is not a trend; it is a scientifically proven method to brake the hyperproliferation of cells. Dermabon’s 2% formula harnesses this capability in a safe, accessible format. It addresses the mechanics of the disease—the speed of growth—rather than just masking the redness.

If you are looking for a treatment for skin plaques that respects the biology of your skin and offers a sustainable path to clearance, the science points to Coal Tar.

Stop Guessing, Start Treating

Your skin needs science, not magic. Use the formula trusted by experts.

  • Active Ingredient: 2% Coal Tar.
  • Action: Inhibits rapid cell growth.
  • Result: Clear, healthy skin.

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